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What is Stickler syndrome?

Stickler syndrome is a genetic condition that affects connective tissues that support and give structure to other organs in your body, primarily in the face, ears, eyes and joints. This hereditary condition can cause facial abnormalities like a cleft palate. The condition can lead to problems with vision, hearing and movement.

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Stickler syndrome is also known as Stickler dysplasia.

Who does Stickler syndrome affect?

Stickler syndrome can affect anyone. People who have a family member with Stickler syndrome are at a higher risk of having the condition. But in some people, a spontaneous genetic change (mutation) causes the condition and there’s no tie to family history.

How common is Stickler syndrome?

Stickler syndrome occurs in roughly 1 to 3 out of 7,500 to 10,000 newborns. The exact rate of occurrence among the general population is unknown because many cases of Stickler syndrome go undiagnosed. In the U.S., Stickler syndrome is one of the most common connective tissue conditions that exists.

How does Stickler syndrome affect my body?

Stickler syndrome affects connective tissues in your body, which are responsible for protecting and supporting other tissues and organs. Because a mutation of a gene responsible for making connective tissue didn’t receive instructions on how to form and function, symptoms of the condition affect how you see, hear and move, targeting your eyes, ears and joints. It’s common for people diagnosed with Stickler syndrome to have arthritis at a young age. Treatment addresses symptoms of Stickler syndrome to allow those diagnosed with the condition to live full and active lives.